My first response is always the same, "what do you like to do".
The conversations begin to vary a bit at that point but rarely do I get a concrete, specific answer. Many times I hear what it is that you don't like or I hear vague responses about helping people.
If you want something different, you must re-discover your strengths and your passions.
It takes some skill and guidance in order to do this in a way that will result in a rewarding, new career. Since this was not my area of expertise, I looked for the best resource I could find so that I could help all of the nurses who approached me during my workshops. I found the book Now, Discover Your Strengths
Before looking for a new job, take some time to get very clear about what it is that you absolutely love to do.
In his workshop (and in the book) he asks you to spend one week and to document those things that you LOVE and LOATHE. Once you have a few things written down, he takes you to the next step...For everything that you LOVE, find a verb that describes what it is that you enjoyed.
For example: when I did this exercise, everything that I loved involved researching, fixing something, or teaching. I also realized that I was in a nearly perfect career for me because that is exactly what I do 80%-90% of the time. What a relief!!
The same applied to the things I loathed. I really don't like managing the details. That's why I need someone to prepare my presentations, and handle my calendar. I found a resource to help me with my weaknesses (those things that make me feel weak).
Before you attempt to change jobs or careers, I highly encourage you to watch the workshop on iTunes or read Now, Discover Your Strengths